The big C - for Chemoprevention : CANCER PREVENTIONSPORN, Michael B.Nature (London). 2011, Vol 471, Num 7339, issn 0028-0836, S10-S11Article

Arzoxifene: A promising new selective estrogen receptor modulator for clinical chemoprevention of breast cancerSPORN, Michael B.Clinical cancer research. 2004, Vol 10, Num 16, pp 5313-5315, issn 1078-0432, 3 p.Article

Is Lycopene an Effective Agent for Preventing Prostate Cancer?SPORN, Michael B; LIBY, Karen T.Cancer prevention research (Philadelphia, Pa.). 2013, Vol 6, Num 5, pp 384-386, issn 1940-6207, 3 p.Article

Transforming growth factor-Bs chemistry, biology, and therapeutics, May 18-20, 1989, Arlington VAPIEZ, KARL A; SPORN, MICHAEL B.Annals of the New York Academy of Sciences. 1990, Vol 593, issn 0077-8923, 390 p.Conference Proceedings

ΔNp63α-Mediated Activation of Bone Morphogenetic Protein Signaling Governs Stem Cell Activity and Plasticity in Normal and Malignant Mammary Epithelial CellsBALBONI, Amanda L; HUTCHINSON, Justine A; DIRENZO, James et al.Cancer research (Chicago, Ill.). 2013, Vol 73, Num 2, pp 1020-1030, issn 0008-5472, 11 p.Article

The synthetic triterpenoid TP-222 inhibits RANKL stimulation of osteoclastogenesis and matrix metalloproteinase-9 expressionFAVA, Roy A; ELLIOTT, Sarah; RAYMOND, Lauren et al.Journal of rheumatology. 2007, Vol 34, Num 5, pp 1058-1068, issn 0315-162X, 11 p.Article

Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1 -[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]lmidazoleYATES, Melinda S; KWAK, Mi-Kyoung; HONDA, Tadashi et al.Cancer research (Baltimore). 2006, Vol 66, Num 4, pp 2488-2494, issn 0008-5472, 7 p.Article

The PARP Inhibitors, Veliparib and Olaparib, Are Effective Chemopreventive Agents for Delaying Mammary Tumor Development in BRCA1-deficient MiceCIRIC TO; KIM, Eun-Hee; ROYCE, Darlene B et al.Cancer prevention research (Philadelphia, Pa.). 2014, Vol 7, Num 7, pp 698-707, issn 1940-6207, 10 p.Article

Anti-inflammatory Triterpenoid Blocks Immune Suppressive Function of MDSCs and Improves Immune Response in CancerNAGARAJ, Srinivas; YOUN, Je-In; SPORN, Michael B et al.Clinical cancer research (Print). 2010, Vol 16, Num 6, pp 1812-1823, issn 1078-0432, 12 p.Article

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated miceYATES, Melinda S; TRAN, Quynh T; LIBY, Karen T et al.Carcinogenesis (New York. Print). 2009, Vol 30, Num 6, pp 1024-1031, issn 0143-3334, 8 p.Article

The Triterpenoid CDDO-Imidazolide Confers Potent Protection against Hyperoxic Acute Lung Injury in MiceREDDY, Narsa M; SURYANARAYA, Vegiraju; YATES, Melinda S et al.American journal of respiratory and critical care medicine. 2009, Vol 180, Num 9, pp 867-874, issn 1073-449X, 8 p.Article

The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistanceCHAUHAN, Dharminder; GUILAN LI; GRIBBLE, Gordon W et al.Blood. 2004, Vol 103, Num 8, pp 3158-3166, issn 0006-4971, 9 p.Article

The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemiaKONOPLEVA, Marina; TSAO, Twee; KANTARJIAN, Hagop et al.Cancer research (Baltimore). 2004, Vol 64, Num 21, pp 7927-7935, issn 0008-5472, 9 p.Article

New Synthetic Triterpenoids: Potent Agents for Prevention and Treatment of Tissue Injury Caused by Inflammatory and Oxidative StressSPORN, Michael B; LIBY, Karen T; YORE, Mark M et al.Journal of natural products (Print). 2011, Vol 74, Num 3, pp 537-545, issn 0163-3864, 9 p.Article

Glycogen Synthase Kinase 3β Regulates Cell Death Induced by Synthetic TriterpenoidsVENE, Roberta; LARGHERO, Patrizia; ARENA, Giuseppe et al.Cancer research (Chicago, Ill.). 2008, Vol 68, Num 17, pp 6987-6996, issn 0008-5472, 10 p.Article

Novel tricyclic compounds having acetylene groups at C-8a and cyano enones in rings A and C : Highly potent anti-inflammatory and cytoprotective agentsHONDA, Tadashi; SUNDARARAJAN, Chitra; YOSHIZAWA, Hidenori et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 8, pp 1731-1734, issn 0022-2623, 4 p.Article

c-Jun NH₂-Terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cellsWEI ZOU; XIANGGUO LIU; PING YUE et al.Cancer research (Baltimore). 2004, Vol 64, Num 20, pp 7570-7578, issn 0008-5472, 9 p.Article

Design and synthesis of tricyclic compounds with enone functionalities in rings A and C: A Novel class of highly active inhibitors of nitric oxide production in mouse macrophagesFAVALORO, Frank G; HONDA, Tadashi; HONDA, Yukiko et al.Journal of medicinal chemistry (Print). 2002, Vol 45, Num 22, pp 4801-4805, issn 0022-2623, 5 p.Article

A synthetic triterpenoid selectively inhibits the induction of matrix metalloproteinases 1 and 13 by inflammatory cytokinesMIX, Kimberlee S; MENGSHOL, John A; BENBOW, Ulrike et al.Arthritis and rheumatism. 2001, Vol 44, Num 5, pp 1096-1104, issn 0004-3591Article

Oral Administration of a Gemini Vitamin D Analog, a Synthetic Triterpenoid and the Combination Prevents Mammary Tumorigenesis Driven by ErbB2 OverexpressionJAE YOUNG SO; WAHLER, Joseph E; NANJOO SUH et al.Cancer prevention research (Philadelphia, Pa.). 2013, Vol 6, Num 9, pp 959-970, issn 1940-6207, 12 p.Article

The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J miceLIBY, Karen; ROYCE, Darlene B; WILLIAMS, Charlotte R et al.Cancer research (Baltimore). 2007, Vol 67, Num 6, pp 2414-2419, issn 0008-5472, 6 p.Article

Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring AHONDA, Tadashi; LIBY, Karen T; GRIBBLE, Gordon W et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 24, pp 6306-6309, issn 0960-894X, 4 p.Article

The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor β-dependent apoptosis in breast cancerRENDI, Mara H; NANJOO SUH; WILLIAMS, Charlotte R et al.Cancer research (Baltimore). 2004, Vol 64, Num 10, pp 3566-3571, issn 0008-5472, 6 p.Article

A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide productionHONDA, Tadashi; HONDA, Yukiko; FAVALORO, Frank G et al.Bioorganic & medicinal chemistry letters (Print). 2002, Vol 12, Num 7, pp 1027-1030, issn 0960-894XArticle

Treatment and Prevention of intraepithelial neoplasia: An important target for accelerated new agent developmentO'SHAUGHNESSY, Joyce A; KELLOFF, Gary J; NELSON, William G et al.Clinical cancer research. 2002, Vol 8, Num 2, pp 314-346, issn 1078-0432Article